KMID : 0356920130640030240
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Korean Journal of Anesthesiology 2013 Volume.64 No. 3 p.240 ~ p.245
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Effect of ketorolac on the prevention of emergence agitation in children after sevoflurane anesthesia
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Kim Deok-Kyu
Doo A-Ram Lim Hyung-Sun Son Ji-Seon Lee Jun-Rae Han Young-Jin Ko Seong-Hoon
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Abstract
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Background: The purpose of this study was to evaluate the effects of ketorolac on the incidence and severity of emergence agitation in children recovering from sevoflurane anesthesia.
Methods: Eighty-five children aged 3 to 7 years were randomly assigned to the control group or the ketorolac group (1 mg/kg ketorolac). The children were evaluated by the Pediatric Anesthesia Emergence Delirium Scale and a four-point agitation scale.
Results: The median agitation scores did not differ significantly between the two groups. The overall incidence of emergence agitation was similar in the two groups (41% in the control group vs. 32% in the ketorolac group, P = 0.526). The number of children who received rescue drugs for treatment of emergence agitation was not significantly different between the two groups.
Conclusions: The administration of 1 mg/kg of ketorolac is not effective in decreasing the incidence and severity of emergence agitation in children aged 3 to 7 years after sevoflurane anesthesia.
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KEYWORD
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Agitation, Anesthesia, Ketorolac, Pediatrics
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